MusclePharm Corporation (OTCBB:MSLP), will begin a clinical research program with the Metabolic and Body Composition Laboratory in the department of Health and Exercise Science at the University of Oklahoma to determine the effects of MusclePharm Assault(R) beginning in January 2011.

The clinical research program will be led by Jeffrey R. Stout, Ph.D, MusclePharm's Scientific Advisor, who is an Associate Professor and Director of the OU lab. Stout, along with other faculty in the department, will study the effects of MusclePharm's products on high-intensity interval training, on aerobic and anaerobic power, repeated sprint ability, body composition, training volume and strength levels.

MusclePharm Assault(R) is rated as a top pre-workout supplement on numerous, premier websites. Scoring 9.2 out of 10 on bodybuilding.com proves Assault(R) to be at the top of its category. With previous assessments and reviews performed by thousands of satisfied customers in conjunction with the research team at the University of Oklahoma, MusclePharm is once again proving themselves as an industry leader.

The research team at the University of Oklahoma has conducted and published numerous studies that focus on nutritional interventions on exercise performance, muscle function and body composition, fueling excitement for MusclePharm and the future potential for the product line.

Headquartered in Denver, Colorado, MusclePharm is a rapidly expanding healthy life-style company that develops and manufacturers a full line of NSF and scientifically approved nutritional supplements that are 100% free of any banned substances.

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Orofino Gold Corp. (ORFG.PK) is a US (Nevada) company established for the purpose of creating a significant exploration and mining group to operate in Colombia.

Orofino has major criteria by which they select properties that includes:

* Significant historical production
* Favorable geology for hosting major ore bodies
* Significant property area for large target exploration
* Recent results available
* Favorable infrastructure and access to allow mine development
* Receptive local government and populace.

In addition, Orofino has acquired a database comprised of exploration and mining results from previous operators who left when the global mining sector experienced a major downturn in the three year period from 1997-2000

The second part of the Company's strategy to become a recognized player in the Colombia mining sector was the acquisition of an interest in an operating mine. The Company has acquired a 55% interest in the La Azul/La Estrella property with the rights to acquire up to 80%.

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Ligand Pharmaceuticals Inc. (Nasdaq:LGNDD) announced data from a preclinical study on the erythropoietin (EPO) receptor agonist LG5640 at the upcoming 52nd American Society of Hematology (ASH) Annual Meeting that was recently held in Orlando, Florida at the Orange County Convention Cente. The poster presentation highlighted the unique mechanism of action and selective profile of LG5640, a novel oral EPO receptor agonist being developed as a more convenient and safer treatment alternative to current erythropoiesis-stimulating agent therapies (ESAs).

Ligand discovers and develops novel drugs that address critical unmet medical needs of patients for a broad spectrum of diseases.

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O’Charley’s Inc. (Nasdaq:CHUX) announced that it has closed 11 underperforming O’Charley’s restaurants and five underperforming Ninety Nine restaurants. David Head, president and chief executive officer of O’Charley’s Inc. said, “Our decision to close these restaurants was a difficult one as we understand the impact this has on our team members and the communities we serve. We deeply appreciate the hard work, passion and enthusiasm of our team members and managers at the affected locations. Everyone impacted by this decision has been offered severance payments, and where geographically feasible we are working hard to find opportunities for these team members at other O’Charley’s and Ninety Nine restaurants, as well as with restaurants operated by our competitors.

O’Charley’s Inc., headquartered in Nashville, Tenn., is a multi-concept restaurant company.

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Marchex, Inc. (Nasdaq:MCHX) announced the availability of a new white paper focusing on digital marketing for small businesses, “Three Things Small Businesses Really Need.” The white paper discusses the challenges and opportunities presented to small businesses in light of the rapid changes in the way consumers are interacting with information online, and how these changes are forcing small business to re-think their approach to marketing.

Marchex’s mission is to unlock local commerce globally by helping advertisers reach customers wherever they may be – in mobile, offline and online channels, including in its own local and category websites.

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Crown Equity Holdings Inc. (CRWE.OB) has received five thousand dollars and anticipates receiving another forty five thousand dollars in cash from a third party for 30 (thirty) days of advertising for MusclePharm Corporation (MSLP.OB)

Crown Equity Holdings Inc. (CRWE.OB) has received 500,000 shares of 144 stock in Orofino Gold Corp. (PINK SHEETS: ORFG) valued at sixty five thousand dollars, and 500,000 shares of free trading shares valued at sixty five thousand dollars from a third party (QU CUI You) for 30 days advertising.